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Should we consider Addison's disease in the differential diagnosis of persistent hypertransaminasemia ? A case report

Journal Volume 74 - 2011
Issue Fasc.1 - Letters
Author(s) Panagiotis Anagnostis, Vasilios G. Athyros, Themistoklis Vasiliadis, Theodora Griva, Kaliopi Patsiaoura, Asterios Karagiannis
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(1) Endocrinology Clinic, Hippokration Hospital, Thessaloniki, Greece ; (2) Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece ; (3) Department of Pathology, Hippokration Hospital, Thessaloniki, Greece.

A 29 year-old Caucasian male was admitted to our department in order to investigate persistent hyper- transaminasemia (3-4-fold the normal values) for at least 1 year, along with a symptomatology of progressive fatigue and weight loss (6 kg/6 months). No remarkable data were revealed from the individual and family histo- ry. Physical examination demonstrated hyperpgimenta- tion, atrophy of the upper and lower limbs, hypotension (100/70 mmHg on supine and 80/50 mmHg on upright position) and enlargement of cervical lymph nodes.

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PMID 21563662